The History Of Nuflor

An Antibiotic So Unique, It’s In A Class By Itself

June 1996

Nuflor receives FDA approval for use in the treatment of bovine respiratory disease (BRD) associated with Mannheimia Pasteurella haemolytica, Pasteurella multocida, and Haemophilus somnus. Its active ingredient, florfenicol, is unlike any other class of antibacterials. Developed exclusively for animal health, Nuflor has a broad spectrum of activity, including activity against resistant organisms.

July 1998

Nuflor receives FDA approval for one-dose subcutaneous administration; dosage is 6 mL per 100 pounds body weight. Its original approval had been for two doses administered intramuscularly two days apart, with a dosage of 3 mL per 100 pounds. The new administration option allows producers the flexibility to use Nuflor according to whichever treatment regimen fits their management practices.

December 1998

Nuflor receives FDA approval for control of respiratory disease in cattle at high risk of developing BRD associated with M. haemolytica, P. multocida, and H. somnus. Dosage is 6 mL per 100 pounds, given in one subcutaneous dose. Since high-risk cattle typically have been exposed to multiple bacteria, the broad-spectrum activity of Nuflor is especially appropriate for this use. Research demonstrates that treatment of high-risk cattle can reduce respiratory pulls by 50%.1

January 1999

Nuflor receives FDA approval for use in the treatment of bovine foot rot associated with Fusobacterium necrophorum and Bacteroides melaninogenius. Dosage and administration are the same as for BRD treatment. Nuflor now offers producers an array of uses: treat BRD according to a one- or two-dose program; control BRD in high-risk cattle, with a one-dose program; and treat foot rot with a one- or two-dose program.

This record of approvals is a clear indication of the excellent efficacy and safety profile of Nuflor. It also is an indication of the commitment of Merck Animal Health to bring superior products to the market, products that improve animal health and benefit cattle producers.

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