In the fall of 2006, a randomized, masked clinical study was conducted at a
contract research organization to determine the effect of NUFLOR (florfenicol) or Baytril
100 (enrofloxacin) treatments on feed intake in clinically ill animals. The intake data was
measured using the Grow Safe feed intake system. In the 60 days following BRD
treatment, animals dosed with NUFLOR (florfenicol) ate on average 21.58 lb/day while
cattle treated with Baytril (enrofloxacin) consumed on average 21.38 lb/day. These
intakes were not statistically different (p=0.68). Additionally, there was no statistical difference in feed intake at 7 days post treatment between the two groups (10.67 vs. 11.01; p=0.62). In this controlled clinical study there were no significant feed intake
differences in animals treated for BRD with either Baytril (enrofloxacin) or NUFLOR (florfenicol).
Design of Trials:
Intake Following BRD Treatment:
After treatment with NUFLOR (florfenicol) or Baytril 100 enrofloxacin), most time periods showed no statistical differences in feed intake. One time period, 40 to 60 d following treatment, approached statistical significance (p = 0.06) with the cattle treated with NUFLOR (florfenicol) exhibiting greater average feed intake (Table 1, Chart 1). Body weights were similar among NUFLOR (florfenicol) and Baytril (enrofloxacin) treated cattle at enrollment, and 20, 40 and 60 d posttreatment.
|Intake 0 to 7 d post trt1||10.67||0.47||11.01||0.47||0.62|
|Intake 0 to 20 d post trt1||13.75||0.41||14.45||0.41||0.24|
|Intake 20 to 40 d post trt1||24.10||0.60||24.28||0.60||0.83|
|Intake 40 to 60 d post trt1||26.98||0.53||25.52||0.53||0.06|
|Intake 0 to 60 d post trt1||21.58||0.31||21.39||0.2||0.69|
|BW at enrolment1||568||6.6||571||6.6||0.73|
|20 d BW||609||8.7||612||8.8||0.77|
|40 d BW||695||11.8||708||11.8||0.44|
|60 d BW||744||14.4||772||4.6||0.18|
1These represent intakes on days that are specific to animals and depend on when they were enrolled.
Copyright © 2008, Intervet Inc. Corporation. All rights reserved. Nuflor is a registered trademark of Intervet Inc. Corporation. Baytril is a registered trademark of Bayer. SPAHNFL- 613C